OPIS was founded in 1998 as a small Italian CRO. Over the past 20 years we have worked with passion and dedication to conquer the trust of clients and the scientific community, learning from each project and challenge convinced that investing in knowledge earns the highest interest. Today, OPIS HQ is the number one Italian CRO, with more than 250 employees. As an international level, OPIS manages both local and international full-service studies thanks to its offices located throughout Europe. From its beginning, OPIS has managed complex and demanding projects in terms of study rationale and design, treatment features and patient characteristics. With time, this has led to the advancement of our main strengths: helping clients single out the best solution by putting forward positive and interesting proposals, flexibility, responsiveness, qualified personnel, cohesive and organized teams, and sustained monitoring of project status. OPIS has always been driven by a passion for research, a thirst for knowledge, and the desire to offer a personalized service that meets client needs without ever breaching the ethical and legal requirements that govern the conduct of clinical studies.